Dammarane-type glycosides from steamed notoginseng

  • 文献类型:   Article
  • 作  者:   LIAO PY, WANG D, ZHANG YJ, YANG CR
  • 关键词:   steamed notoginseng, panax notoginseng, dammarane, notoginsenosides st1st3 st5
  • 出版物名称:   JOURNAL OF AGRICULTURAL FOOD CHEMISTRY
  • ISSN:   0021-8561 EI 1520-5118
  • 通讯作者地址:   Chinese Acad Sci
  • 被引频次:   46
  • DOI:   10.1021/jf073000s
  • 出版年:   2008
  • 研究对象:   药化成分
  • 研究主题:   分离合成测定

▎ 摘  要

Notoginseng, the root of Panax notoginseng (Burk.) F.H. Chen (Araliaceae), is a Chinese traditional medicine, which is used in both raw and processed forms due to their different pharmacological activities. Detailed chemical investigation on steamed notoginseng led to the isolation of 27 dammarane-type triterpenoids (1-27), including 4 new glycosides, namely, notoginsenosides ST-1-ST-3 and ST-5 (1-4), in addition to 3 other known compounds. Of the new compounds, 1-3 possess new aglycones. Their structures were elucidated on the basis of detailed analyses of their 1 D and 2D NMR spectra and chemical reactions. The known compounds, koryoginsenoside-R-1 (19), yesanchinoside D (20), 6 ''-O-acetylginsenoside Rg(3) (24), and 3 beta,6 alpha,12 beta-trihyclroxyclammar-20(21),24-diene (25), were isolated from notoginseng for the first time.

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